London Irish administrator Lee Manning says it is only "a matter of time" until the next Premiership club goes bust and that "radical change" is needed.
Twins Tom and Ben Curry will start together for England for the first time in the side that takes on Ireland in Saturday's Six Nations opener at the Aviva Stadium.
Saracens missed out on the chance to book a Champions Cup round of 16 home tie as Castres produced a stunning victory in London.
Tom Willis surged over for two tries as Saracens dispatched second-placed Bristol Bears in a 35-26 victory in the Gallagher Premiership on Saturday.
Sale Sharks pulled off a brilliant 38-0 victory over Bristol Bears at Ashton Gate to move into the Gallagher Premiership play-off places.
Bristol sent out a major title statement as Pat Lam's men set a new Premiership record in a thumping 54-24 win over Leicester at Welford Road.
Defending champions Northampton suffered a shock defeat to Gloucester, while Bath returned to top of the Premiership and Sale beat Leicester.
Sale Sharks and England forward Jonny Hill has received a 10-week ban - with four weeks suspended - after accepting a charge that he abused a spectator.
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