Pool sink Darlo to go top
Eifion Williams fired the home side in front after just three minutes, but Ian Clark replied for the visitors in the 27th minute.
Williams restored Hartlepool's lead with his second after 35 minutes and Ritchie Humphrey's added a third just before the hour mark.
Mark Tinkler wrapped up the win for Chris Turner's side with the fourth seven minutes from time.
Rushden & Diamonds drop down to second after being held to a goalless draw at York.
Rochdale remain in third after a 1-1 draw with Shrewsbury at Spotland.
Jason Van Blerk had given the visitors a surprise lead six minutes before the break but Rochdale player-manager earned his side a point with a 79th equaliser from the penalty spot.
Lincoln missed the chance to move into second spot after being held to a 1-1 draw Leyton Orient.
Ben Futcher fired the visitors in front after 75 minutes but Lee Thorpe's last minute strike earned the home side a point.
Bury kept up the pressure on the leaders with an impressive 2-1 win over ten-man Bournemouth.
Bournemouth were reduced to ten men when Wade Elliott was sent-off for deliberate handball a minute before the break and from the resulting penalty Martyn Forrest fired the visitors in front.
Lee Unsworth doubled the lead in the 56th minute to put them in firm control.
Gareth O'Connor pulled one back for the home side after 71 minutes.
Torquay continued their rich vein of form with a 3-2 win over Cambridge.
David Graham netted the opener for the home side four minutes before the break and Kevin Hill added a second in the 62nd minute.
Graham grabbed his second seven minutes later to wrap up the win for Torquay.
Cambridge's misery was compounded when Warren Goodhind was sent-off eight minutes from time for violent conduct.
Shane Tudor pulled two back for the visitors in stoppage time, but it was not enough to prevent Torquay from taking all three points.
Wrexham took the spoils in their Wales derby with Swansea with a convincing 4-0 win at the Racecourse Ground.
A quick-fire brace from Andy Morrell (10,12) put the hosts in firm control and Hector Sam added a third on the half hour. Carlos Edwards completed the rout with the fourth in the 56th minute.
Oxford piled the misery on Division Three new boys Boston with a 3-1 victory at York Street to leave The Pilgrims rooted to the bottom of the table.
Paul Powell gave the visitors the lead after 16 minutes and a double from Andy Scott (24, 36) put the game beyond Boston.
Veteran midfielder Neil Redfearn grabbed a consolation for the home side after 55 minutes.
Hull netted their first home win of the season with a comprehensive 4-0 victory over Carlisle at Boothferry Park with Gary Alexander the star of the show with a fine hat-trick
Alexander grabbed his first of the game after 20 and he added a second four minutes after the break.
He completed his treble in the 73rd minute and Lawrie Dudfield added a fourth after 78 minutes to seal the points for Jan Molby's minutes.
Scott Brough's 70th minute goal earned Scunthorpe a 1-1 draw with Kidderminster.
Sam Shilton had fired the visitors in front right on the stroke of half time, but Brough's goal meant the spoils were shared. Southend moved into eighth spot with a narrow 1-0 win over Macclesfield at Roots Hall.
Leon Cort hit the only goal of the game after 26 minutes to give the home side all three points.
Bristol Rovers moved out of the bottom three with a 1-1 draw with Exeter at the Memorial Ground.
Steve Flack fired the visitors in front after 27 minutes, but Paul Tait drew the sides level six minutes before the break.
Click on fixture for full match summary
Boston 1-3 Oxford
Bournemouth 1-2 Bury
Bristol Rovers 1-1 Exeter
Hartlepool 4-1 Darlington
Hull 4-0 Carlisle
Leyton Orient 1-1 Lincoln
Rochdale 1-1 Shrewsbury
Scunthorpe 1-1 Kidderminster
Southend 1-0 Macclesfield
Torquay 3-2 Cambridge
Wrexham 4-0 Swansea
York 0-0 Rushden
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